impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.
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I think that it depends per country. In my country we have a The Job Is Done We Can Go Home Now Nikola Jokic Shirt of Saint Nicolas. His day on the ecclesiastical calendar is the 6th of December. But the Saintly Bishop arrives in our country around the 15th of November. That is also the moment that the High Streets get their decorating lights. Days are short it gets dark shortly after four o’clock. The decorations in the shops are focused on Saint Nicholas. Special sweets and presents for children. There are special children shows on television. When I was a child we were invited to come to the head office of my father’s employer, Unilever, for a special afternoon with a magician and of course a visit by the saint Nicholas himself, with his assistants Zwarte Piet. (Black Peter) At the end we were given a nice small present, chosen of course by our parents (but of course we did not know). After the 6th of December when Saint Nicholas had returned to Spain or Heaven, the shops turn on to Christmas decorations. Some times we see some imported Fathers Christmas but we do not have narratives about father Christmas.
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